The SLC22A2 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to SLC22A2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The SLC22A2 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline(norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide(NMN), tetraethylammonium(TEA), 1-methyl-4-phenylpyridinium(MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity